Figure 1

Metabolic pathw ays for synthesis of PC in P. falciparum.
PC, phosphatidylcholine; PE, phosphatidylethanolamine; PS: phosphatidylserine. The CDP-choline pathway is shown is black arrows and the SDPM pathway is gray arrows. Cho, choline; CDP, cytidine diphosphate; CDP-cho, CDP-choline; CCT: CTP:phosphocholine cytidylyltransferase; ECT: CTP:phosphoethanolamine cytidylyltransferase;Ser: serine; Etn: ethanolamine; CDP-Etn, CDP-ethanolamine; EK: ethanolamine kinase; CK: choline kinase; PSS: PS synthase; PSD: phosphatidylserine decarboxylase; ECT; CEPT: CDP-choline/ethanolamine: 1,2 diacylglycerol choline/ethanolamine phosphotransferase; SD: serine decarboxylase (SD gene is unknown).