Figure 10 | Scientific Reports

Figure 10

From: Structure, Function and Inhibition of the Phosphoethanolamine Methyltransferases of the Human Malaria Parasites Plasmodium vivax and Plasmodium knowlesi

Figure 10

Stereo representation of a pairwise alignment of PvPMT:SAM:PO4 (green, PDB code: 4IV0) and PkPMT:SAM (pink, PDB code: 4IV8) with PfPMT:SAH:PO4 (cyan, PDB code: 3UJ6) RMSD = 0.452 Å.

Proteins represented as ribbon Cα trace, SAM and PO4 as spheres. The AQ binding site and interacting residues based on crystal structure reported here are in supplemental figures 3 and 4.

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