Table 1 Kinetic parameters of PkPMT and PvPMT enzymes

From: Structure, Function and Inhibition of the Phosphoethanolamine Methyltransferases of the Human Malaria Parasites Plasmodium vivax and Plasmodium knowlesi

Enzyme/Substrate

Vmax (nmolmin−1 mg−1Protein)

Kcat (min−1)

Km (mM)

Kcat/Km (min −1mM−1)

PvPMT/P-Etn

18.67 ± 2.93

0.05 ± 0.01

0.21 ± 0.07

0.28

PvPMT/SAM

12.62 ± 0.95

0.04 ± 0.02

0.23 ± 0.07

0.17

PkPMT/P-Etn

86.01 ± 8.35

0.26 ± 0.02

0.10 ± 0.03

2.6

PkPMT/SAM

119.7 ± 15.41

0.37 ± 0.03

0.27 ± 0.09

1.37

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