Figure 3 | Scientific Reports

Figure 3

From: Structure based aggregation studies reveal the presence of helix-rich intermediate during α-Synuclein aggregation

Figure 3

Duration of helix-rich intermediates is dependent on the aggregation propensity of α-Syn.

(A) Duration of helix and lag time for different synucleins follows a linear correlation. (B) Concentration dependent aggregation kinetics of WT α-Syn measured by ThT binding assay. (C) Corelation plot for the lag time and duration of helix for WT α-Syn at different concentration (1 mM, 600 μM and 300 μM). Duration of helical intermediate is lowest for 1 mM and longest for 300 μM concentration of α-Syn.

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