Figure 5
Injection of paternal (i.e., sperm-borne) and maternal (i.e., oocyte) total RNAs induced the “white-tail-tip” (WTT) phenotype.
(A) Incidence of the WTT phenotype among offspring derived from WT BTT zygotes injected with WT BTT sperm-borne RNAs. Note that all mice used were WT BTT males or females. (B) Incidence of the WTT phenotype among offspring derived from WT BTT zygotes injected with WT BTT oocyte RNAs. Note that all mice used were WT BTT males or females. (C) Incidence of the WTT phenotype among offspring derived from WT BTT parents-derived zygotes injected with sperm-borne RNAs isolated from HET (Kit+/copGFP) males. (D) Incidence of the WTT phenotype among offspring derived from WT BTT parents-derived zygotes injected with oocyte RNAs isolated from HET (Kit+/copGFP) females. (E) Outcrossing F1 males or females carrying sperm-borne RNA-induced WTT phenotype with WT BTT females and males, respectively. “n” denotes the total number of offspring observed in each of the mating schemes (A–E).
