Table 3 The identified DNBs are the modules with high influence appearing in both the control and case networks at each time point for the four datasets. The common genes identified by other methods were noted in bold

From: Deciphering deterioration mechanisms of complex diseases based on the construction of dynamic networks and systems analysis

Datasets

Modules

Genes in the corresponding module

GSE30550

HM1

{DDX58; HERC5; HERC6; IFI27; IFI35; IFI44; IFI44L; IFI6; IFIH1; IFIT1; IFIT2; IFIT3; IRF7;IRF9;ISG15;MX1;OAS1;OAS2;OAS3; OASL; RSAD2; XAF1}

GSE52428

HM2

{ADAR; DDX58; GBP1; GBP2; HERC5; HERC6; IFI27; IFI35; IFI44; IFI44L; IFI6; IFIH1; IFIT1; IFIT2; IFIT3; IFIT5; IFITM1; IRF1; IRF7; IRF9; ISG15; MX1; MX2; OAS1; OAS2; OAS3; OASL; RSAD2; RTP4; XAF1}

GSE2565

HM3

{Bnip3; Esd; Hk2; Aldoa; Ldha; Pgd; Pgk1; Pkm2; Taldo1; Tkt; Tpi1;Arhgef12; Pard6b; Prkci; Rhoj; Rhou; Pkp3; Ppl; Scel; Gtf2f2; Pcf11; Papolg; Ptbp1; Thoc4; U2af1}

GSE13268

HM4

{Akr1b7; Fah; Glrx1; Gpx7; Gss; Gsta3; Gstm2; Gstm5; Gstm7; Gsto1; Gsto2; Gstp1; Gstt1; Gstt2; Mgst2;Nit1; Prdx3; Xdh; Ankrd6; Frzb; Fzd1; Acpl2; Lef1; Nkd1; NlkSox17; C6; Ermp1; Ppap2c; Sgms1; Smpd2; Smpd3; Cyp11a1; Cyp11b1; Tmem50b; Hsd11b2; Fdx1l}