Figure 5
From: Circulating Peptidome to Indicate the Tumor-resident Proteolysis
Peptide sequences and the relative expression levels of the two C3f fragments in serum (SSATTFRL and LWENGNLLR) were determined and quantified using iTRAQ.
Serum peptides from mice treated with MSV-control siRNA were labeled with 114, whereas serum peptides from mice treated with MSV-EphA2 siRNA were labeled with 115. (A) The b- and y-ion series indicate the sequence of SSATTFRL and a zoomed-in view (B) shows its reporter ion region at m/z = 114.1 and 115.1. (C) The b- and y-ion series indicate the sequence of LWENGNLLR and a zoomed-in view (D) shows its reporter ion region at m/z = 114 and 115.
