Table 2 MIC values (μg/mL) for KIA peptides in four different bacterial strains. Inactive peptides are marked in bold for each strain

From: Hydrophobic mismatch demonstrated for membranolytic peptides and their use as molecular rulers to measure bilayer thickness in native cells

Peptide

Gram-negative

Gram-positive

 

E. coli

P. aeruginosa

S. aureus

E. faecalis

KIA14

>256

>256

>256

>1024

KIA15

>256

>256

>256

>1024

KIA17

32

256

256

>1024

KIA19

32

256

>256

>1024

KIA21

4

64

8

1024

KIA22

4

32

16

1024

KIA24

4

16

4

64

KIA26

4

16

8

64

KIA28

8

16

8

16

PGLa (control)

32

256

64

>1024