Figure 5
From: Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor
Decrease of a2V is associated with reduction of LAMP-2 in the RAW 264.7 mouse macrophage cell line.
RAW 264.7 cells were treated for 30 min with PBS, PGN+poly(I:C) or LPS, followed by up to 2 h incubation with IgG control or anti-a2V antibody. (A) mRNA expression of a2V; (B) protein for LAMP-2 (green) and a2V (red); (C) LAMP-2 in the absence or presence of an a2V neutralizing antibody. Original magnification: 400X. Each experiment was done three times with triplicates. Error bars = ±SEM. **P ≤ 0.01 Significant difference vs. respective control.
