Figure 4
Estimating the parasite multiplication rate in naive and acutely infected mice.
Fitting the data on the growth of the GFPpos PbA parasite population with the model of parasite growth with age-independent clearance yields these estimates of parasite clearance, which depend on the multiplication rate, β0 (solid lines are the median for each group, shaded regions indicate the range of estimates within each group). For each value of β0 clearance rates for the acutely infected mice are higher than those for the naïve mice. When fitting the disappearance curves of infected donor cells from the same hosts we estimated a clearance rate for each group of mice (dashed lines are the medians for each group). The points of intersection of the solid and dashed lines for each group of mice provide an estimate of the parasite multiplication rate β0 for each group of mice. We observe that a lower parasite multiplication rate is estimated in the acutely infected mice than in the naïve mice.
