Figure 5

Minocycline enhanced the expression of M2 markers by minocycline treatment in the hippocampus of young offspring rats.
The expression of M2 markers (Arg1, Ym1, IL-4, IL-10 and CD206) decreased in the MSD offspring rats. These decreases were improved by minocycline administration in the MSD offspring (Figs. 5a–5e). * P < 0.05, ** P < 0.01 vs. control-saline. # P < 0.05, # # P < 0.01 vs. MSD-saline. $ P < 0.05 vs. con-mino. Values are the mean ± SEM.