Figure 3
From: Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications
Binding of hexa-Fc to human DC-SIGN by multi-channel surface plasmon resonance analysis (MC-SPR).
Association and dissociation curves of Igs binding to recombinant human DC-SIGN immobilized on a sensor chip. Hexa-Fc (panels b,d), IVIg GammaGard (panel e), dimeric-Fc (panel f) or gp120 control (panels a,c) were injected at doubling dilutions as indicated into flow at time 0 and replaced with buffer at 300 sec. Data are representative of duplicate experiments.
