Figure 5
From: Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier
The transgene protects against dextran sodium sulfate (DSS)-induced colitis.
(a). Wild-type (WT; n = 11) and transgenic (Tg, n = 9) mice were treated with 2.5% DSS or phosphate-buffered saline (PBS) for 5 days and then received water for 7 days. Body mass was scored daily. (b). Histological score76 was calculated at day 12. (c). Proliferating cell nuclear antigen (PCNA) immunostaining of colon sections and its quantification showed an increase in epithelial cell proliferation in Tg mice.
