Figure 5 | Scientific Reports

Figure 5

From: Increased signaling entropy in cancer requires the scale-free property of proteininteraction networks

Figure 5

Entropy rate increase in cancer requires the scale-free topology of the PPInetwork:

(A) Boxplots of the entropy rate (SR) for the 50 normal liver and 50 livercancer samples as evaluated on the original full PPI network (left), as wellas on an equivalent Erdos-Renyi graph (middle). P-values are from aWilcoxon-rank sum test. Corresponding ROC curves and AUC values (right). (B)As A) but for TCGA RNA-Seq data from 27 colon cancers and 27 matchednormals. (C) As A) but for TCGA RNA-Seq data from 52 prostate cancers and 52matched normals.

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