Figure 3
From: Structure of Slitrk2–PTPδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion
Recognition of PTPδ meB by Slitrk2 LRR1.
(a) SPR equilibrium analysis of the interaction between Slitrk2 LRR1 and the splicing variants or mutants of PTPδ Ig1-Fn1. Slitrk2 LRR1 was immobilized on a CM5 sensor tip and the indicative PTPδ Ig1-Fn1 proteins were injected. Response units were plotted against concentrations of the indicative PTPδ Ig1-Fn1 proteins. (b) SPR equilibrium analysis of the interaction between Slitrk2 LRR1 mutants and PTPδ Ig1-Fn1 (meA9/meB+). (c)Dissociation constants calculated from (a) and (b).
