Figure 2
From: KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines
FRET stabilization temperatures (ΔTm) of KRAS21R G4 and hairpin ds-DNA (T-loop) at 0.2 μM, in K-cacodylate buffer (pH = 7.4, 60 mM K+), stabilized by IQc derivatives and TMPyP4 at 1 μM.
a) SD ≤ 0.2°C.
