Figure 3
From: KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines
FRET melting competition assay data for (a) 2d and (b) 3e (1 μM) in complex with KRAS21R and F21T G4s (0.2 μM), with increasing concentrations of non-labeled 26ds, HT21 or KRAS21R (0.4 to 25 μM) competitor, in K-cacodylate buffer (pH 7.4, 60 mM K+).
