Table 4 Urine drug test for amphetamine use, morphine use and methadone dose and Mean Opiate Treatment Index (OTI) at baseline and after 12 weeks of treatment

From: Low-dose add-on memantine treatment may improve cognitive performance and self-reported health conditions in opioid-dependent patients undergoing methadone-maintenance-therapy

 

Baseline

 

Post-Treatment

 
 

MMT+P

MMT+M

χ2/T (p)

MMT+P

MMT+M

χ2/T (p)

Urine test

      

 Amphetamine use (+/−)

9/33

2/37

4.58 (0.03)

9/33

4/35

1.87 (0.17)

 Morphine use (+/−)

24/17

22/14

0.05 (0.82)

19/21

19/15

0.52 (0.47)

Methadone dose (mg/day)

35.37 ± 20.04

39.73 ± 21.31

−0.93 (0.35)

43.38 ± 25.66

37.35 ± 22.62

1.10 (0.28)

 

(SE = 3.13)

(SE = 3.50)

 

(SE = 4.22)

(SE = 3.58)

 

Opiate Treatment Index (OTI)

     

 Heroin Q score

1.21 ± 1.30

1.05 ± 1.20

0.43

0.37 ± 0.77

0.54 ± 1.22

−0.76 (0.45)

 

(SE = 0.22)

(SE = 0.21)

(0.66)

(SE = 0.13)

(SE = 0.21)

 

 Opiate Q Score

0

0

--

0

0

--

 Crime1 Q Score

0

0.06 ± 0.35

−1.04

0

0

--

  

(SE = 0.06)

(0.30)

   

 Health2 Q Score

5.42 ± 4.23

4.59 ± 4.48

0.85

4.11 ± 4.65

3.25 ± 3.14

0.90 (0.37)

 

(SE = 0.71)

(SE = 0.79)

(0.40)

(SE = 0.77)

(SE = 0.56)

 
  1. 1Criminality: number of crime offended in four crime areas: property crime, dealing, fraud and crimes involving violence.
  2. 2Health: The higher the score, the poorer the overall health of the subject.
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