Figure 6 | Scientific Reports

Figure 6

From: The proto-oncogene survivin splice variant 2B is induced by PDGF and leads to cell proliferation in rheumatoid arthritis fibroblast-like synoviocytes

Figure 6

The serum expression levels of survivin-2B in RA patients determined using an ELISA. (a) We collected serum samples from 35 RA patients and 21 age- and sex- matched controls (healthy controls and OA patients) and measured the serum survivin-2B levels with an ELISA (mean RA, 18.7 ng/ml vs. controls, 4.7 ng/ml; p = 0.049) (RA, 64.7 ± 11.4 years old; controls, 59.6 ± 18.0 years old; p = 0.250). The gray lines indicate the median of survivin-2B level in each group. (b) We compared the DAS28-ESR between the survivin-2B high RA group (n = 18) and the survivin-2B low RA group (n = 21) (mean RA, 4.64 vs. controls, 3.64; p = 0.037). t-test, ∗p < 0.05.

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