Figure 2 | Scientific Reports

Figure 2

From: Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel

Figure 2

Pharmacological activities of BmKTX-19 on different potassium channels.

A–H, Current traces in the absence (control) or presence of 1 nM BmKTX-19 on Kv1.3 and 1 μM BmKTX-19 on Kv1.1, Kv1.2, Kv7.1, Kv11.1, KCa2.2, KCa2.3 and KCa3.1 channels, respectively. I, Normalized current inhibition by various concentrations of BmKTX-19 on Kv1.3 channels. Data represent the means ± S.E. of at least three experiments.

Back to article page