Figure 3 | Scientific Reports

Figure 3

From: Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel

Figure 3

Pharmacological activities of BmKTX-196 on different potassium channels.

A–H, Current traces in the absence (control) or presence of 10 nM BmKTX-196 on Kv1.3 and 1 μM BmKTX-196 on Kv1.1, Kv1.2, Kv7.1, Kv11.1, KCa2.2, KCa2.3 and KCa3.1 channels, respectively. I, Normalized current inhibition by various concentrations of BmKTX-196 on Kv1.3 channels. Data represent the means ± S.E. of at least three experiments.

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