Figure 5
From: Multiple myeloma acquires resistance to EGFR inhibitor via induction of pentose phosphate pathway
Genetic inhibition of G6PD showed similar effects to 6AN.
A) LP-1 cells transfected with G6PD shRNA showed decreased G6PD to a similar extend to 6AN; B) Combination of Gefitinib or Afatinib with either genetic G6PD silencing or 6AN showed similar effects on cell proliferation.
