Figure 1 | Scientific Reports

Figure 1

From: MicroRNA-33b Inhibits Breast Cancer Metastasis by Targeting HMGA2, SALL4 and Twist1

Figure 1

miR-33b is downregulated in breast cancer tissue samples and breast cancer cell lines.

(A) qRT-PCR analysis of miR-33b expression in human breast cancer tissue samples and their matched normal breast tissues from 29 breast cancer patients. (B) In situ hybridization analysis of miR-33b expression in human breast cancer tissues and matched normal tissues. (C) Correlation between miR-33b expression and the progression of the clinical stage of breast cancer. (D) Correlation between miR-30b expression and the lymph node metastasis status of breast cancer. (E) Correlation between clinicopathological features and miR-33b expression in 29 breast cancer tissues. (F) qRT-PCR analysis of miR-33b expression in noncancerous human mammary epithelial cells and breast cancer cell lines with different metastatic potential. Scale bars, 50 μm. Data represent the mean ± s.d. **: P <0.01, ***: P <0.001.

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