Figure 2 | Scientific Reports

Figure 2

From: Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Caused by a Novel R782G Mutation in CSF1R

Figure 2

Axial T2-weighted images including the corpus callosum and peri-rolandic white matter.

The MRI shows multifocal involvement of the corpus callosum with volume loss, particularly posteriorly. There is asymmetric white matter involvement with sparing of the sub-cortical u-fibres. White matter deep to the pre-central and post-central gyri is specifically involved. No signal change is found within the pyramidal tracts more inferiorly. In places there is apparent involvement of white matter lying transverse to the long axis of the lateral ventricles. Otherwise there is mild cerebellar volume loss, mild parietal and frontal atrophy. The brainstem is normal.

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