Figure 6
Comparison for target engagement of MS0 analogues in cell lysate and in intact cell.
(A) CESTA melt curves in cell lysate for NAMPT target with MS7 (at 100 μM). (B, C) ITDRFCETSA at 62 °C in cell lysate (B) or in intact cell (C) for NAMPT target with MS1 or MS7.
