Figure 4 | Scientific Reports

Figure 4

From: Optogenetic stimulation of mPFC pyramidal neurons as a conditioned stimulus supports associative learning in rats

Figure 4

A period of time is required for stable performance of CR.

(a–c) Top: training and testing scheme. Bottom: modification of intertrial interval (ITI) had significant effect on trials to criterion (b), but had no effect on CR% (a) or latency to criterion (c; n = 9 rats each; N.S., not significant, *P < 0.05, ***P < 0.001; one-way ANOVA followed by Tukey post-hoc test). (d–f) Top: training and testing scheme. Bottom: modification of the proportion of habituation and conditioning training had no effect on CR% (d), trials to criterion (e), or latency to criterion (f; n = 9 rats for 0-trial Hab., control and 40-trial Hab. groups, n = 8 rats for 20-trial Hab. group and n = 9 rats for 30-trial Hab. group; N.S., not significant, one-way ANOVA followed by Tukey post-hoc test). Data are represented as mean ± s.e.m.

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