Table 3 Adjusted HRs for dementia in the OA and non-OA cohorts determined using the frailty model.
From: Osteoarthritis Increases the Risk of Dementia: A Nationwide Cohort Study in Taiwan
Presence of dementia during the 4-year follow-up period | |||
---|---|---|---|
Crude HR (95% CI) | Adjusted HR (95% CI) | P value for adjusted HR | |
OA | 1.32 (1.17–1.49) | 1.21 (1.07–1.38) | 0.002 |
Age (year) | 1.09 (1.08–1.10) | 1.08 (1.07–1.09) | <0.001 |
Sex (M) | 0.90 (0.79–1.02) | 0.73 (0.65–0.83) | <0.001 |
Autoimmune disease | 1.22 (0.95–1.55) | 1.14(0.90–1.46) | 0.299 |
DM | 1.73 (1.53–1.96) | 1.25 (1.10–1.42) | <0.001 |
Hypertension | 2.57 (2.24–2.95) | 1.06 (0.92–1.23) | 0.381 |
Hyperlipidaemia | 0.98 (0.86–1.12) | 0.92 (0.80–1.05) | 0.218 |
Coronary heart disease | 1.85 (1.63–2.09) | 0.94 (0.82–1.07) | 0.342 |
Parkinson’s disease | 8.44 (7.26–9.82) | 2.98 (2.54–3.49) | <0.001 |
COPD | 2.15 (1.91–2.42) | 1.27 (1.12–1.44) | <0.001 |
Stroke | 6.58 (5.83–7.43) | 3.14 (2.75–3.58) | <0.001 |