Table 1 Genotype distribution of TNF-α-308G > A in controls and patients with BC.
Category | GG | GA + AA | OR (95% CI) | P | ||
|---|---|---|---|---|---|---|
n | (%) | n | (%) | |||
Controls (n= 565) | 484 | 85.7 | 81 | 14.3 | 1.00 | |
All BC (n= 768) | 668 | 87.0 | 100 | 13.0 | 0.89 (0.63–1.25) | 0.482 |
IHC subtype | ||||||
TNBC (n= 163) | 147 | 90.2 | 16 | 9.8 | 0.67 (0.38–1.19) | 0.133 |
Her2+ (n= 82) | 71 | 86.6 | 11 | 13.4 | 0.90 (0.41–1.72) | 0.812 |
Luminal A (n= 183) | 165 | 90.2 | 18 | 9.8 | 0.67 (0.33–1.14) | 0.120 |
Luminal B (n= 340) | 285 | 83.8 | 55 | 16.2 | 1.20 (0.84–1.77) | 0.523 |
ER and PR status | ||||||
ER+ (n= 523) | 450 | 86.1 | 73 | 13.9 | 0.98 (0.68–1.36) | 0.852 |
ER− (n= 245) | 218 | 89.0 | 27 | 11.0 | 0.72 (0.43–1.18) | 0.204 |
PR− (n= 585) | 503 | 86.0 | 82 | 14.0 | 0.92 (0.65–1.34) | 0.867 |
Her2+ (n= 686) | 597 | 87.0 | 89 | 13.0 | 0.86 (0.63–1.35) | 0.531 |
