Table 2 Characteristics of studies included in the pooled meta-analysis.
Ethnicity | Study | Samples (cases/controls) | Genotyping Method | Cases | Controls | PHWE (controls) | ||||
|---|---|---|---|---|---|---|---|---|---|---|
GG | GA | AA | GG | GA | AA | |||||
Caucasian | Chouchane, 1997 | 40/106 | ASPCR | 15 | 24 | 1 | 72 | 33 | 1 | 0.183 |
Mestiri, 2001 | 243/174 | PCR-RFLP | 167 | 53 | 23 | 117 | 53 | 4 | 0.480 | |
Giordani, 2003 | 125/100 | PCR-RFLP | 104 | 19 | 2 | 84 | 15 | 1 | 0.721 | |
Azmy, 2004 | 705/498 | TaqMan | 475 | 208 | 22 | 313 | 167 | 18 | 0.458 | |
Kamali-Sarvestani, 2005 | 223/235 | ASO-PCR | 192 | 31 | 0 | 203 | 32 | 0 | 0.263 | |
Scola, 2006 | 84/106 | PCR-RFLP | 71 | 12 | 1 | 79 | 26 | 1 | 0.472 | |
Gaudet, 2007 | 5156/4983 | TaqMan | 3679 | 1345 | 132 | 3488 | 1368 | 127 | 0.604 | |
Gonullu, 2007 | 38/24 | PCRS-SPM | 30 | 6 | 2 | 15 | 9 | 0 | 0.258 | |
Sirotkovic-Skerlev, 2007 | 158/76 | TaqMan | 136 | 22 | 0 | 68 | 8 | 0 | 0.628 | |
MARIE-GENICA, 2010 | 3138/5476 | MALDI-TOF MS | 2237 | 822 | 79 | 3795 | 1528 | 153 | 0.957 | |
Karakus, 2011 | 204/204 | ASO-PCR | 167 | 36 | 1 | 159 | 45 | 0 | 0.077 | |
Madeleine, 2011 | 869/900 | SNPlex system | 603 | 245 | 21 | 613 | 264 | 23 | 0.388 | |
Gómez Flores-Ramos, 2013 | 465/294 | PCR-RFLP | 302 | 96 | 67 | 254 | 38 | 2 | 0.660 | |
Asian | Park, 2002 | 95/190 | PCR-RFLP | 75 | 20 | 0 | 134 | 54 | 2 | 0.174 |
Kohaar, 2009 | 40/150 | PCR-RFLP | 21 | 16 | 3 | 211 | 24 | 2 | 0.170 | |
Pooja, 2011 | 200/200 | Sequencing | 179 | 19 | 2 | 166 | 34 | 0 | 0.189 | |
Xu, 2014 | 1016/806 | PCR-RFLP | 927 | 89 | 0 | 716 | 89 | 1 | 0.300 | |
This study | 768/565 | TaqMan | 668 | 97 | 3 | 484 | 78 | 3 | 0.940 | |
