Figure 6
SL327 induced apoptosis mainly in neuron and oligodendrocyte.
(a–g) Double immunostaining of activated caspase-3 with cellular markers for neuron (a, b), astrocyte (c, d) and oligodendrocyte (e–g). Activated caspase-3 signals were observed in neuron (a, b) but not in astrocyte 6 h (c, d) after SL327 injection at P6. Activated caspase-3 signals were also observed in oligodendrocytes in the cortex and white matter (e, f), but not in the subiculum (g). Scale bar: 50 μm.
