Figure 5
From: Inherently Stealthy and Highly Tumor-Selective Gold Nanoraspberries for Photothermal Cancer Therapy
Mechanism of internalization studies
Two-photon luminescence (TPL) of GRBs were measured using three different breast cancer cell lines SKBR-3, BT-549, MCF-7 and compared with MCF-10A, breast epithelial cells (A) Light micrscopy images of SKBR-3, MCF-10A, BT-549 and MCF-7 cell lines using the phase contrast mode after GRBs internalization in both passive and active targeting (B) TPL images of the same cell lines, which clearly indicated SKBR-3 cells exhibit maximum photoluminescence with active targeting whereas nonspecific adsorption was observed in control MCF-10A cells.
