Figure 3
Pathway enrichment of overlapping AS genes.
The enrichment analysis of pathways through gene set association was conducted for each gene set. Each node within the network represents a significant gene set belonging to a pathway. The number of edges of a pathway node corresponds to the number of risk genes overlapped with that particular pathway gene set. The size of the node corresponds to the p-value. The mapped green nodes represent overlapping significant pathways between AS (red node) and other immune mediated diseases (blue node). The range of p-values for the overlapping pathways is indicated next to each disease group. The most significant top two pathways that overlap with AS risk genes are displayed below the p-value.
