Figure 1 | Scientific Reports

Figure 1

From: Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model

Figure 1

Schematic diagram of the orthotopic retinoblastoma model in zebrafish.

Human and mouse retinoblastoma cells are cultured in RPMI-1640 and subconfluent tumor cells are harvested and labeled with DiI dye (red). Labeled tumor cells were intravitreally implanted in a single eye of each zebrafish. Tumor cell invasion, dissemination and distal metastasis can be visualized under fluorescent microscopy in the body of living zebrafish.

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