Figure 4 | Scientific Reports

Figure 4

From: Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy

Figure 4

ADTM inhibited the expression of P-selectin.

Whole blood was treated with DMSO (0.1%) as a control or the indicated concentrations of ADTM (1–100 μM) for 5 min at 37 °C. After that the platelets were activated using ADP (10 μM). Flow cytometry histogram (a) and the quantification of the data (b) show that ADTM inhibits P-selectin binding to ADP-activated platelets. #P < 0.01 compared with the control group, *P < 0.01 compared with the ADP group. Data are representative of three independent experiments.

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