Figure 3
From: Identification of a distinct population of CD133+CXCR4+ cancer stem cells in ovarian cancer
CXCR4+CD133+ ovarian cancer cells possess resistance to chemotherapy, migration and colony forming capabilities.
OVCAR-5 sorted cells (A) Cytotoxicity assay in the presence of Cisplatin (0, 5, 10M). (B) QPCR analysis of ABCG2. (C) Migration assay toward CXCL12 and (D) Clonogenic assay. A representative photograph is provided in the lower panel. (*p < 0.05, **p values < 0.001, compared with the CD133-CXCR4- group).
