Figure 4

Evaluation of different doses of Cy5.5-exendin-3 in vivo.
(a) Representative images of the fluorescence signal and the corresponding xfOCM images 4 hours after injection of different doses of Cy5.5-exendin-3. Scale bar: 200 μm. (b,c) Quantification of fluorescence islet intensity (b) and exocrine fluorescence intensity (c) 4 hours after injection of different doses of Cy5.5-exendin-3 (0.1, 1, 14 μg), control (ctrl) and blocking (block.).* p < 10−4, ** p < 10−5, Mann-Whitney non-parametric U-test.