Figure 1 | Scientific Reports

Figure 1

From: Prognostic significance of kynurenine 3-monooxygenase and effects on proliferation, migration and invasion of human hepatocellular carcinoma

Figure 1

Up-regulation of KMO in HCC tissues.

(A) Western blotting analysis for KMO in 10 paired samples of HCC tissues (T) and matched adjacent non-tumorous liver tissues (N). Left panel Representative Western blots for KMO and β-actin were shown. Right panel Band intensities of KMO were normalized to β-actin and showed as T/N Fold Change. Uncropped full-length blots for A are shown in the Supplementary Fig. 1. (B) IHC staining of KMO in 50 pairs of HCC tissues (T) and matched adjacent non-tumorous liver tissues (N) (Test cohort). (C) Integrated optical density (IOD) for KMO was obtained from the test cohort. (D) IHC staining of KMO in 70 pairs of HCC tissues (T) and matched adjacent non--tumorous liver tissues (N) (Validation cohort). (E) IOD for KMO was obtained from the validation cohort.

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