Figure 3

Schematic (a) and graphical representation (b) of the complexation and dissociation of MACP6/c-kitG20T as inferred from temperature dependent CD spectroscopic studies. Here, CD signal changes at 380 nm of MACP6 (4 μM) and c-kitG20T (8 μM) in 17 mM phosphate buffer solution (5% DMSO) at 20 °C (represented as“⚬”) and 60 °C (represented as“•”) were used to monitor the switching “on” and “off” of the molecular switch.