Figure 5 | Scientific Reports

Figure 5

From: G-quadruplex induced chirality of methylazacalix[6]pyridine via unprecedented binding stoichiometry: en route to multiplex controlled molecular switch

Figure 5

The CD Job-plot corresponding to the binding between MACP6 and G-quadruplex of a) c-kitG20T, b) c-mycTGA-de in 17 mM phosphate buffer solution (5% DMSO) at 20 °C. [MACP6] + [G-quadruplex] = 12 μM. The similar maximum value of y (defined as the CD intensity value of the MACP6/G4 complex) at 380 nm was found at 0.33 for c-kitG20T or c-mycTGA-de, a finding consistent with a 1:2 (MACP6: G4) binding stoichiometry.

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