Table 1 Basic characteristics of all patients and univariate survival analysis.

From: Ratio of C-Reactive Protein/Albumin is An Inflammatory Prognostic Score for Predicting Overall Survival of Patients with Small-cell Lung Cancer

Variables

Cases, N

Proportion, %

Median OS, months (95% CI)

P value b

Age, years

59 (23-82)a

  

0.049

Gender

 Male

316

86.1

16.7(14.75-18.65)

0.077

 Female

51

13.9

18.7(11.61-27.39)

 

Smoking

 Smoker

302

82.3

16.8(14.69-18.91)

0.917

 Never-smoker

65

17.7

16.0(12.61-19.33)

 

Disease stage

 Limited stage

180

49.0

22.1(17.10-27.10)

<0.001

 Extensive stage

187

51.0

14.2(11.61-16.72)

 

PS

 0

195

53.1

17.0(15.01-19.06)

<0.001

 1

142

38.7

18.7(16.14-21.20)

 

 2

30

8.2

9.3(7.94-10.73)

 

CRP/Alb

 ≥0.441

128

34.9

13.7(11.86-15.61)

0.005

 <0.441

239

65.1

18.9(16.93-20.87)

 

LDH, U/L

Normal range

220

59.9

19.2(17.52-20.89)

<0.001

 Abnormally elevated

147

40.1

13.3(11.06-15.61)

 

Chemotherapy regimen

 Etoposide-based

315

85.8

17.2(15.34-19.13)

0.685

 Others

52

14.2

13.2(7.31-19.16)

 

Prophylacticcranial irradiation

0.361

 Yes

81

22.1

16.2(12.85-19.55)

 

 No

286

77.9

17.0(15.08-18.99)

 
  1. Note: aMedian (range); bLog-rank test
  2. Abbreviations: OS, overall survival; CI, confidence interval; PS, performance status; CRP/Alb, C-reactive protein/albumin; LDH, lactate dehydrogenase