Figure 1
From: Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice
NPC1L1 and microbiota.
(A) Average wet weight of ceca and cecum-to-body weight (BW) ratios in SPF and GF mice treated with or without ezetimibe (n = 10(11). (B) Relative abundance of bacterial phyla in feces of L1-KO mice and their wild-type (WT) controls on a chow diet or a high fat diet (HFD) for 5 weeks (n = 4 for L1-KO/Chow, WT/Chow and WT/HFD; n = 3 for L1-KO/HFD). Analysis was done by pyrosequencing of 16S rRNA genes. (C) Stool output in SPF and GF mice treated with or without ezetimibe (n = 10–11). The values with different small letters differ significantly (One-way ANOVA, p < 0.05). WD, Western diet; Ezet, ezetimibe.
