Table 1 Genotype association study of the IFNA10 and IFNA4 variants in expanded CD cases versus controls.

From: Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn’s disease patients

Locus

Groups

n

Genotype frequency [n(%)]

X 2

P

   

T/T (%)

T/A (%)

A/A (%)

  

IFNA4 (c.60 A > T)

CD

208

0 (0)

166 (79.81)

42 (20.19)

7.738

0.005

 

Health group

198

0 (0)

134 (67.68)

64 (32.32)

  

IFNA10 (c.60 T > A)

CD

208

48 (23.1)

160 (76.9)

0 (0)

11.902

0.001

 

Health group

198

77 (38.9)

121 (61.1)

0 (0)