Table 3 Association of IFNA10 variant with responses to medical treatment in CD Patients.
Therapies | CD [n] | Efficacy | Genotype frequency [n(%)] | P | ||
|---|---|---|---|---|---|---|
T/T (%) | T/A (%) | A/A(%) | ||||
5-ASA | 44 | Effective 20 | 8 (40.0) | 12 (60.0) | 0 | 0.911 |
Ineffective 24 | 10 (41.7) | 14 (58.3) | 0 | |||
Steroids | 27 | Effective 10 | 6 (60.0) | 4 (40.0) | 0 | 0.027 |
Ineffective 17 | 2 (11.8) | 15 (88.2) | 0 | |||
Immunosuppressant | 9 | Effective 5 | 2 (40.0) | 3 (60.0) | 0 | 1.000 |
Ineffective 4 | 2 (50.0) | 2 (50.0) | 0 | |||
IFX | 24 | Effective 14 | 6 (42.9) | 8 (57.1) | 0 | 0.889 |
Ineffective 10 | 4 (40.0) | 6 (60.0) | 0 | |||
Overall effects | 47 | Effective 24 | 13 (54.2) | 11 (45.8) | 0 | 0.008 |
Ineffective 23 | 3 (13.1) | 20 (86.9) | 0 | |||
