Figure 4
From: Live Cell Characterization of DNA Aggregation Delivered through Lipofection
Influence of DNA Size on Lipoplex Aggregation.
(A) Size-dependent aggregation of DNA lipoplexes formed in solution. Quantification of average (blue line) and maximum (red line) brightness using N&B methods. (B) 8 and 24 hours after delivery of various sized DNA fragments into myoblasts (n = 6 cells in each group). Box and whisker plots show the IQR with the whiskers providing the upper and lower ranges observed. The red line in the box represents the mean value. Statistical analysis between the different DNA sizes has been presented in Supplementary Figure 4. ns = no significantly difference, * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p < 0.0001.
