Figure 6

Comparison of inhibition activities of six proteins in normal adults (a), non-HFMD children (b) and severe HFMD cases (c). The percent inhibition of competitive ELISA was plotted on the y-axis with six inhibitor proteins on the x-axis: EV71 VP1, VP141-297, VP11-60, VP145-58, VP161-297 and pET32a. The data on the y-axis represent the inhibition of six proteins to coating antigens described in the “Methods” section. The boxes represent the interquartile range, the line inside each box represents the median of the samples and the whiskers represent the range of the data. Statistical significance was tested using Nemenyi non-parametric test. * represent p < 0.05, ** represent p < 0.001. # p < 0.001 comparing the five inhibitor proteins.