Table 1 Qualification of the necrosis in BEL-7402 xenograft tumors in mice.

From: Molecularly Targeted Therapy of Human Hepatocellular Carcinoma Xenografts with Radio-iodinated Anti-VEGFR2 Murine-Human Chimeric Fab

Categorization

Level of necrosis

χ2

P

−

+

++

+++

  

PBS

7

1

0

0

33.253

<0.0001

FA8H1

4

4

0

0

  

131I

5

2

1

0

  

Low dose of 131I-FA8H1

0

1

3

4

  

Medium dose of 131I-FA8H1

0

1

1

6

  

Large dose of 131I-FA8H1

0

0

2

6

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