Table 1 ACH-11 inhibited ADP-induced acute pulmonary thrombosis in mice.

From: A Novel Direct Factor Xa Inhibitory Peptide with Anti-Platelet Aggregation Activity from Agkistrodon acutus Venom Hydrolysates

Samples

Dose for mice (mg/kg)

Numbers of lethal/total

Protection rate (%)

P values (compared with vehicle)

Vehicle

 

9/10

10

 

Aspirin

20

2/10

80**

0.0055

ACH-11

0.33

7/10

30

0.5820

 

1

4/10

60*

0.0198

 

3

1/10

90**

0.0011

  1. Note: **P < 0.01, *P < 0.05 versus vehicle, n = 10 (χ2 test).
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