Figure 5

DotIc forms ring-like oligomers in crystals.
(A) Molecular packing of DotIc in the P21212 crystal. The molecules in an asymmetric unit are shown by ball models with different colors and other symmetry related molecules are indicated by Ca backbone trace. The unit cell is shown by black line. (B) The ribbon diagram of the DotIc octamer ring in the crystal. (C) Size exclusion chromatogram of DotIC in a crystallization condition. Elution profile of DotIC oligomer and monomer is shown with the molecular weight estimated by MALS. The molar masses corresponding to the oligomer and the monomer throughout the elution peaks are shown by the blue and red lines, respectively.