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Figure 1

From: Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library

Figure 1

Study of polymerase read-through of single triazole junction.

A) Scheme for substrate synthesis and read-through study. B) LC trace of control read-through experiment using Klenow with wild-type template. UV detection at 495 nm. C) LC trace of read-through products using Superscript IIITM. D) LC trace of read-through using Klenow fragment. E) Mass spectrum of major peak in trace D).

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