Figure 3
From: Revealing Missing Human Protein Isoforms Based on Ab Initio Prediction, RNA-seq and Proteomics
Validation summary of KNOWN and novel transcripts.
A. shows the number of KNOWN and novel transcripts validated by each RNA-seq dataset using standard or stringent strategy. The highest two points in each group represent validated numbers from GROUP II datasets (RNA-seq data sequenced from the 16 tissues mixture). B. shows validated KNOWN and novel transcript numbers using the standard or stringent strategy grouped by numbers of validated datasets. C and D show the extra numbers of validated KNOWN and novel transcripts using standard or stringent strategy when a new RNA-seq dataset was added. This process was simulated 1,000 times using a bootstrapping strategy.
